What is hyperalgesia?
Hyperalgesia is increased pain from a stimulus that is normally painful.30International Association for the Study of Pain (IASP). Classification of Chronic Pain, 2nd Edition (Revised). Seattle, WA: IASP Press; 2012. p7.
Primary hyperalgesia occurs in injured tissue (for example, tenderness after a cut), whereas secondary hyperalgesia is seen in adjacent undamaged tissue due to sensitization within the CNS and can be assessed with a sharp object.31Cohen SP, Mao J. Neuropathic pain: mechanisms and their clinical implications. BMJ. 2014 Feb 5; 348:f7656, p4.
What causes hyperalgesia?
Current evidence suggests that hyperalgesia is a consequence of damage to the nociceptive system. 30
What is hypoalgesia?
Hypoalgesia is defined as a diminished sensation of pain in response to normally painful stimuli.32International Association for the Study of Pain (IASP). Classification of Chronic Pain, 2nd Edition (Revised). Seattle, WA: IASP Press; 2012. P8.
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